Wound Healing

Wound Healing Problems

Wounds generally heal in 4 to 6 weeks. Chronic wounds are those that fail to heal within this timeframe. Many factors can lead to impaired healing. The primary factors are hypoxia, bacterial colonization, ischemia, reperfusion injury, altered cellular response, and collagen synthesis defects. Any failure in the normal wound healing process results in abnormal scar formation, and chronic state which is more susceptible to infections. Chronic wounds affect patients’ quality of life and thus requires specialized biomedical intensive treatment for its management. The clinical assessment and management of chronic wounds remains challenging despite the development of various therapeutic regimens owing to its painstakingly long-term treatment requirement and complex wound healing mechanism.

Phases of Wound Healing

The wound-healing process consists of four highly integrated and overlapping phases: hemostasis, inflammation, proliferation, and tissue remodeling or resolution. These phases and their biophysiological functions must occur in the proper sequence, at a specific time, and continue for a specific duration at an optimal intensity. There are many factors that can affect wound healing which interfere with one or more phases in this process, thus causing improper or impaired tissue repair.

What is Wound Healing Regeneration vs Repair?

Regeneration involves restitution of tissue components; repair involves “patching” rather than restoring. Repair leads to scar formation. The amount of regeneration vs. repair that occurs depends on the proliferative capacity of the cells, the integrity of the connective tissue cells and the duration of the injury and inflammatory response.

What to Expect from Therapy

Wound healing requires an interaction among different cell types, building proteins and growth factors. However, if the natural wound healing process is disrupted, the wound can become hard-to-heal due to a lack of growth factors and cytokines that play a role in the wound healing process. We use an autologous gold induced serum to support the activation and differentiation of cells by the help of certain cytokines. With this treatment we support the body´s regeneration potential for faster and full wound closure.

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